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Cisco ISR4221/K9 Integrated Services Router

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ISR4221/K9 Overview

Cisco 4221 Integrated Services router is design to deliver advanced services to the small enterprise branch environment. It delivers 35Mbps thoughtput by default. With pay-as-you-grow performance, you can increase forwarding capacity to 75Mbps by buying licenses.

Quick Specs

Table 1 shows the Quick Specs.

Product Code

Cisco

ISR4221/K9

Aggregate Throughput

35 Mbps to 75 Mbps

Total onboard WAN or LAN 10/100/1000 ports

2

RJ-45-based ports

2

SFP-based ports

1

NIM (Network Interface Modules) slots

2

Onboard ISC slot

No

Default memory double-data-rate 3 (DDR3) error-correction-code

(ECC) DRAM (Combined control/services/data planes)

4 GB

Flash Memory

8 GB

Power-supply options

External AC only

Rack height

1 RU

Dimensions (H x W x D)

1.72 x 12.7 x 10 in (43.7 x 322.6 x 254 mm)

Weight with AC PS (no modules)

7.1 lb (3.22 kg)
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Aggregate Throughput

35 Mbps to 75 Mbps

Total onboard WAN or LAN 10/100/1000 ports

2

RJ-45-based ports

2

SFP-based ports

1

Enhanced service-module slots

0

Doublewide service-module slots

0

NIM slots

2

OIR (all I/O modules)

No

Onboard ISC slot

No

Default memory double-data-rate 3 (DDR3) error-correction-code (ECC) DRAM

(Combined control/services/data planes)

4 GB

Maximum memory DDR3 ECC DRAM (Combined control/services/data planes)

4 GB

Default memory DDR3 ECC DRAM (data plane)

NA

Maximum memory DDR3 ECC DRAM (data plane)

NA

Default memory DDR3 ECC DRAM (control/services plane)

NA

Maximum memory DDR3 ECC DRAM (control/services plane)

NA

Default flash memory

8 GB

Maximum flash memory

8 GB

External USB 2.0 slots (type A)

1

USB console port -type B mini (up to 115.2 kbps)

0

Serial console port - RJ45 (up to 115.2 kbps)

1 (combo CON/AUX port)

Serial auxiliary port - RJ45

(up to 115.2 kbps)

1 (combo CON/AUX port)

Power-supply options

External: AC Only

Redundant power supply

N/A

AC input voltage

100 to 240 VAC autoranging

AC input frequency

47 to 63 Hz

AC input current range, AC power supply (maximum)

1.5 to 0.6A

AC input surge current

90 A peak and less than 3 Arms per half cycle

Typical power (no modules) (watts)

24

Maximum power with AC power supply (watts)

90

Maximum power with PoE power supply (platform only) (watts)

NA (no PoE support)

Maximum endpoint PoE power available from PoE power supply (watts)

NA (no PoE support)

Frequently Asked Questions

What is Cisco ISR4221/K9?

The Cisco ISR4221/K9 is an enterprise branch router from the Cisco 4000 Series designed for secure WAN connectivity in small and medium branch offices. It provides integrated routing, modular expansion, and enterprise-grade reliability for distributed networks.

What is the throughput of ISR4221/K9?

The ISR4221/K9 supports 35 Mbps to 75 Mbps aggregate throughput, which makes it ideal for small branch offices handling typical business applications, secure internet access, and WAN connectivity.

What ports and interfaces does ISR4221/K9 include?

Key interfaces include: 2 × Gigabit Ethernet WAN/LAN ports 1 × SFP port 2 × NIM slots for expansion USB and console management ports This modular design allows businesses to add interfaces as their network grows.

Does ISR4221/K9 support VPN and secure connectivity?

Yes. The router supports secure WAN architecture and enterprise VPN deployment when paired with appropriate licensing, making it suitable for branch-to-HQ communication and protected cloud access.

Is ISR4221/K9 end-of-sale or still supported?

The ISR4221/K9 is end-of-sale, but Cisco still provides support until 30 November 2028, which is frequently searched by enterprise buyers planning lifecycle upgrades.

ISR4221/K9 good for branch office deployments?

Yes. Cisco designed ISR4221 specifically as a branch router for enterprise environments, providing stable WAN routing, modular upgrade capability, and secure connectivity for remote offices.

What is the replacement for ISR4221/K9?

Cisco’s recommended upgrade path is the Cisco Catalyst C8200L-1N-4T, offering: Modern SD-WAN architecture Higher performance capability Longer lifecycle support Better cloud application optimization This is one of the most searched migration questions for ISR users.

What is the difference between ISR4221/K9 and ISR4221-SEC/K9?

Main difference: ISR4221/K9 → Base routing model (IP Base) ISR4221-SEC/K9 → Includes additional security license bundle Businesses choose the SEC model when advanced security features are required out of the box.

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